cees dekker - An Overview
cees dekker - An Overview
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2009, discovery of a completely new phenotype for bacteria in narrow nanofluidic slits; and initial detection of neighborhood protein constructions alongside DNA employing stable-condition nanopores
Our team reports bacterial cell division and it is aiming to represent a ‘base up biology’ in synthetic cells that may autonomously divide. Our primary desire lies in mobile division, chromatin construction, and spatial Manage.
, Groningen scientists existing the effects in their efforts to create labs a lot more sustainable and provide guidelines for other labs.
Because 2000, Dekker has shifted the leading focus of his perform to biophysics exactly where he reports the Attributes of single biomolecules and cells using the instruments of nanotechnology. This alteration of area was pushed by his fascination with the outstanding operating of Organic molecular buildings, as well as from the extended-expression standpoint that numerous fascinating discoveries could be anticipated With this industry.[five] Present-day strains of study in his biophysics group are within the regions of:[six]
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Immediate immobilization of native yeast iso-one cytochrome c on bare gold: quick electron relay to redox enzymes and zeptomole protein-movie voltammetry
We condition micro organism into kinds that deviate from their organic phenotype. Especially, I will show our ability to condition Stay E. coli microorganisms into novel shapes such as rectangles, squares, triangles and circles.
2000, discovery that nanotubes can have incredible big latest densities; resolved the controversial concern of Digital transportation via DNA molecules by measurements of insulating habits at the single molecule degree; and demonstration of the AFM system for single-molecule manipulation of nanotubes
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Resolving the phase measurement in condensin-driven DNA loop extrusion identifies ATP binding since the stage-producing method
An built-in microfluidic ceesdekker.net System for quantifying drug permeation across biomimetic vesicle membranes
Quite a few new phenomena had been discovered, and he and his investigation group recognized a leading position Within this subject of study. Dekker and his exploration group learned new physics of nanotubes along with explored the feasibility of molecular electronics. In 1998, they had been the very first to construct a transistor determined by only one nanotube molecule.
2005, discovery from the system of DNA uncoiling by topoisomerase enzymes; discovery of extensive-assortment conformational variations in Mre11/DNA fix complexes; and to start with force measurements over a DNA molecule inside of a nanopore
‘I'm pushed by wonder and concerns. On a fabric degree I uncover responses in physics, but I working experience my deepest happiness with God. That faith also drives my science and how I cope with folks.